Copied!

Pathway Search



NAD metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
nicotinic_acid_mononucleotide + diphosphate + CO2 <=> 5-phospho-alpha-D-ribose_1-diphosphate + quinolinic_acid + H+ 2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating)

(ADP-ribose)n + NAD+ <=> (ADP-ribose)n + nicotinamide + H+ 2.4.2.30 NAD+ ADP-ribosyltransferase
2.4.2.31 NAD+---protein-arginine ADP-ribosyltransferase


H2O + NAD+ <=> H+ + ADP-ribose + nicotinamide 2.4.2.30 NAD+ ADP-ribosyltransferase
3.2.2.5 NAD+ glycohydrolase
3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
3.5.1




NADH + H2O <=> AMP + NMNH + H+ 3.6.1.18 FAD diphosphatase
3.6.1.22 NAD+ diphosphatase
3.6.1.45 UDP-sugar diphosphatase
3.6.1.55 8-oxo-dGTP diphosphatase
3.6.1.9 nucleotide diphosphatase





nicotinamide + H2O <=> NH3 + nicotinate 3.5.1.13 aryl-acylamidase
3.5.1.19 nicotinamidase
3.5.1.4 amidase



NAD+ + ATP <=> H+ + NADP+ + ADP 2.7.1.23 NAD+ kinase

NAD+ + NADPH <=> NADH + NADP+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
1.6.1.3 NAD(P)+ transhydrogenase
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase




nicotinate + 5-phospho-alpha-D-ribose_1-diphosphate + ATP + H2O <=> nicotinic_acid_mononucleotide + diphosphate + ADP + phosphate 6.3.4.21 nicotinate phosphoribosyltransferase

NH3 + ATP + deamido-NAD+ <=> H+ + AMP + diphosphate + NAD+ 6.3.1.5 NAD+ synthase
6.3.5.1 NAD+ synthase (glutamine-hydrolysing)


L-aspartate + O2 <=> H+ + iminosuccinate + H2O2 1.4.3.16 L-aspartate oxidase

ATP + deamido-NAD+ + L-glutamine + H2O <=> H+ + L-glutamate + AMP + diphosphate + NAD+ 6.3.1.5 NAD+ synthase
6.3.5.1 NAD+ synthase (glutamine-hydrolysing)


H+ + NMN + ATP <=> NAD+ + diphosphate 2.7.1.22 ribosylnicotinamide kinase
2.7.7.1 nicotinamide-nucleotide adenylyltransferase
2.7.7.18 nicotinate-nucleotide adenylyltransferase



iminosuccinate + dihydroxyacetone_phosphate <=> quinolinic_acid + H2O + phosphate 2.5.1.72 quinolinate synthase

NMN + H2O <=> beta-D-ribosylnicotinamide + phosphate 3.1.3
3.1.3.2 acid phosphatase
3.1.3.5 5'-nucleotidase
3.6.1.22 NAD+ diphosphatase
3.6.1.45 UDP-sugar diphosphatase





nicotinic_acid_mononucleotide + ATP + H+ <=> deamido-NAD+ + diphosphate 2.7.7.1 nicotinamide-nucleotide adenylyltransferase
2.7.7.18 nicotinate-nucleotide adenylyltransferase


NMN + H2O <=> NH3 + nicotinic_acid_mononucleotide 3.5.1.42 nicotinamide-nucleotide amidase

NMN + H2O <=> D-ribose_5-phosphate + nicotinamide + H+ 3.2.2.14 NMN nucleosidase
3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase


Visualization of the pathway